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Independent Publications

Publications

2024
25.
 Pd Catalyzed Asymmetric Reductive Heck Cyclization of Di-/Tri-/Tetra- substituted Fluoro Tethered Acrylamides.
Manuscript  under preparation

24. gem-Difluoroallene (DFA): An Emerging Versatile Synthetic Precursor to Enable Diverse Fluorinated Molecules.

Kota Sathish, Swati Jain, Naveen Sihag, and M Ramu Yadav* 
Org. Biomol. Chem. 202422, 8078-8096
(Invited article: Celebrating the 100th birthday of Professor Sukh Dev)


23. Pd-Catalyzed Cascade Heck/C(sp3)-H Activation for Spirocyclopropyl Oxindoles.  
Saleem Hafeez†, Ruchi Sharma†, Swati Jain†, Naveen Sihag, Hemaang Bhartiya and M Ramu Yadav* 
Org. Lett. 2024, 26, 5069-5073

22. Pd-Catalyzed Double Heck and Heck-Suzuki Cascade-Reaction of N-(o-Bromoaryl) CF3-Acrylamides.
Ruchi Sharma, Naveen Sihag, Hemaang Bhartiya, Shivangi Saini, Ashish Kumar and M Ramu Yadav* 
Org. Chem. Front. 2024, 11, 1736-1741

21. Harnessing Photocatalytic and Electrochemical Approaches for C-H Bond Trifluoromethylation and Fluoroalkylation.
Ranjay Shaw†, Naveen Sihag†, Hemaang Bhartiya† and M. Ramu Yadav* 
Org. Chem. Front. 2024, 11, 954-1014
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2023
20. Ligand-free Pd-catalyzed double Heck reaction of N-(o-bromoaryl)acrylamides with α-F/CF3-acrylates.
Ruchi Sharma, Swati Jain†, Naveen Sihag†, M Ramu Yadav* 
Chem. Commun. 2023, 59, 8945-8948

19. Cu(I)/N,N-Imine Ligand Catalyzed C(sp3)–C(sp) Coupling of Alkyl Bromides with Alkynes: Scope and Mechanistic Investigation.

Swati Jain, Anmol, Ruchi Sharma, Tarak Karmakar and M. Ramu Yadav* 
Org. Lett. 2023, 25,  5437–5442

18.
Photoinduced Alkyl/Aryl Radical Cascade for the Synthesis of Quaternary CF3-Containing Oxindoles and Indoline Alkaloids.
Ranjay Shaw†; Naveen Sihag†; Swati Jain; Ruchi Sharma; M. Ramu Yadav* 
J. Org. Chem. 2023, 88, 5652–5660

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2022
17. Cu(II)-Catalyzed Unsymmetrical Dioxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-phenoxyketones.
Suvajit Koley; Kaylee T. Cayton; Gisela A. González-Montiel; M. Ramu Yadav; Douglas L. Orsi; Andrew J. Intelli; Paul Ha-Yeon Cheong; Ryan A. Altman 
J. Org. Chem. 2022, 87, 10710–10725

2021

16. Recent developments in decarboxylative C(aryl)–X bond formation from (hetero)aryl carboxylic acids.
Ruchi Sharma, M. Ramu Yadav* 
Org. Biomol. Chem. 2021,19, 5476-5500

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Post-doctorate Publications
 
15. Organocatalytic strategy for hydrophenolation of gem-difluoroalkenes
Douglas L.Orsi, M. Ramu Yadav,
 Ryan A. Altman*  
Tetrahedron 2019, 75, 4325-4336.
[Special Symposium in Print in Honor Professor Stephen Buchwald's 2018 Tetrahedron Prize]


14. “Reductive De-nitration of Nitroarenes”

Myuto KashiharaM. Ramu Yadav, and Yoshiaki Nakao* 
Org. Lett. 2018, 20, 1655.
 
13. “The Buchwald–Hartwig Amination of Nitroarenes”
Fumiyoshi Inoue, Myuto Kashihara, M. Ramu Yadav, and Yoshiaki Nakao*
Angew. Chem. Int. Ed. 2017, 56, 13307.
*Selected as “Hot Paper” by Editors and Highlighted in Angew. Chem. Int. Ed.

12. “The Suzuki–Miyaura Coupling of Nitroarenes”

M. Ramu Yadav,  Masahiro Nagaoka†, Myuto KashiharaRong-Lin ZhongTakanori MiyazakiShigeyoshi Sakaki* , and Yoshiaki Nakao*
J. Am. Chem. Soc. 2017,139, 9423 (†Equally Contributed).*Most Accessed Paper 07-2017 to 12-2017*Highlighted in Synfacts, Angew. Chem. Int. Ed. and Featured in Synform

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PhD Publications
 
11. “Ruthenium-Catalyzed ortho-C–H Mono- and Di-imidation of Arenes with N-Tosyloxyphthalimide”
M. Ramu YadavMajji ShankarE. RameshKoushik Ghosh, and Akhila K. Sahoo*
Org. Lett. 2015, 17, 1886 (†Equally Contributed).


10. “Sulfoximine Assisted Pd(II)-Catalyzed Bromination and Chlorination of Primary β-C(sp3)–H Bond”

Raja K. RitM. Ramu YadavKoushik GhoshMajji Shankar, and Akhila K. Sahoo*
Org. Lett. 2014, 16, 5258.

9. “Sulfoximine-Directed Ruthenium-Catalyzed ortho-C–H Alkenylation of (Hetero)Arenes: Synthesis of EP3 Receptor Antagonist Analogue” 

M. Ramu YadavRaja K. RitMajji Shankar, and Akhila K. Sahoo*
J. Org. Chem. 201479, 6123.

9. “Sulfoximine-Directed Ruthenium-Catalyzed ortho-C–H Alkenylation of (Hetero)Arenes: Synthesis of EP3 Receptor Antagonist Analogue” 

M. Ramu YadavRaja K. RitMajji Shankar, and Akhila K. Sahoo*
J. Org. Chem. 201479, 6123.

8. “Pd(II)-Catalyzed ortho-C–H Oxidation of Arylacetic Acid Derivatives: Synthesis of Benzofuranones”

Raja K. RitM. Ramu Yadav, and Akhila K. Sahoo*
Org. Lett. 2014, 16, 968.

7. “Ru(II)-Catalyzed Intermolecular Ortho-C-H Amidation of Aromatic Ketones with Sulfonyl Azides”

M. BhanuchandraM. Ramu YadavRaja K. RitMalleswara Rao Kuram and  Akhila K. Sahoo*
Chem. Commun. 2013, 49, 5225.

6 “Sulfoximine Directed Intermolecular o-C–H Amidation of Arenes with Sulfonyl Azides”

M. Ramu YadavRaja K. Rit, and Akhila K. Sahoo*
Org. Lett. 2013, 15, 1638. *Highlighted in Synfacts

5. “Pd(II)-Catalyzed Primary-C(sp3)–H Acyloxylation at Room Temperature”

Raja K. RitM. Ramu Yadav, and Akhila K. Sahoo*
Org. Lett. 2012, 14, 3724.

4. “Sulfoximines: A Reusable Directing Group for Chemo- and Regioselective ortho C-H Oxidation of Arenes”

M. Ramu YadavRaja K. Rit and Akhila K. Sahoo*
Chem-Eur J. 2012, 18, 5541.

Reviews and Book Chapter

3. “Ruthenium-Catalyzed C-N and C-O Bond Forming Process from C-H Bond Functionalization”
S. Dana, M. Ramu Yadav and Akhila K. Sahoo*
TOMC Springer 2016 “C-H Bond Activation and Catalytic Functionalization I” Vol. 55, pp 189-215 2015 (Invited Book Chapter).
 

2. “Reusable Directing Groups for sp2 C-H Bond Functionalization of Arenes”

M. Ramu Yadav, Raja K. Rit, Majji Shankar and Akhila K. Sahoo*

Asian J. Org. Chem. 2015, 4, 846 (Invited review).

​

1. “Reusable directing groups [8-aminoquinoline, picolinamide, sulfoximine] in C(sp3)–H bond activation: present and future”

Raja K. Rit, M. Ramu Yadav, Koushik Ghosh and Akhila K. Sahoo* Tetrahedron, 2015, 71, 4450 (Invitation in honor of Prof. Yoshiaki Nakao on his being awarded Tetrahedron Young Investigator Award-2015).

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